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Vivek Subbiah Selected Research

pralsetinib

1/2022Addressing challenges with real-world synthetic control arms to demonstrate the comparative effectiveness of Pralsetinib in non-small cell lung cancer.
10/2021Hallmarks of RET and Co-occuring Genomic Alterations in RET-aberrant Cancers.
6/2021The L730V/I RET roof mutations display different activities toward pralsetinib and selpercatinib.
1/2021Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study.
1/2021Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study.
10/2020Responsiveness to immune checkpoint inhibitors versus other systemic therapies in RET-aberrant malignancies.
10/2020State-of-the-Art Strategies for Targeting RET-Dependent Cancers.
1/2018Precision Targeted Therapy with BLU-667 for RET-Driven Cancers.

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Vivek Subbiah Research Topics

Disease

177Neoplasms (Cancer)
04/2022 - 07/2007
24Sarcoma (Soft Tissue Sarcoma)
01/2022 - 03/2010
22Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 07/2015
18Disease Progression
01/2022 - 09/2008
16Melanoma (Melanoma, Malignant)
02/2022 - 01/2010
15Neoplasm Metastasis (Metastasis)
01/2022 - 04/2011
11Ewing Sarcoma (Sarcoma, Ewing)
01/2022 - 04/2009
10Osteosarcoma (Osteogenic Sarcoma)
10/2021 - 07/2011
9medullary Thyroid cancer
01/2022 - 02/2015
9Thrombocytopenia (Thrombopenia)
01/2022 - 06/2015
8Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 12/2014
8Diarrhea
01/2022 - 05/2012
7Prostatic Neoplasms (Prostate Cancer)
01/2021 - 01/2014
7Thyroid Neoplasms (Thyroid Cancer)
01/2021 - 01/2017
6Cholangiocarcinoma
02/2022 - 01/2013
6Nausea
10/2021 - 05/2012
5Lung Neoplasms (Lung Cancer)
02/2022 - 10/2019
5Neutropenia
10/2021 - 06/2015
5Vomiting
10/2021 - 05/2012
5Exanthema (Rash)
01/2021 - 01/2017
5Breast Neoplasms (Breast Cancer)
01/2021 - 01/2014
5Hodgkin Disease (Hodgkin's Disease)
11/2020 - 11/2007
5Hypertension (High Blood Pressure)
01/2020 - 01/2017
5Fatigue
01/2019 - 10/2016
5Desmoplastic Small Round Cell Tumor
10/2018 - 04/2011
4Carcinoma (Carcinomatosis)
01/2022 - 03/2020
4Anaplastic Thyroid Carcinoma
01/2022 - 08/2015
4Renal Cell Carcinoma (Grawitz Tumor)
11/2020 - 02/2015
4Anemia
11/2018 - 10/2016
3Biliary Tract Neoplasms (Biliary Tract Cancer)
02/2022 - 01/2020
3Microsatellite Instability
01/2022 - 01/2019
3Carcinogenesis
10/2021 - 08/2019
3Leiomyosarcoma
10/2021 - 12/2016
3Ovarian Neoplasms (Ovarian Cancer)
10/2021 - 08/2015
3Small Cell Lung Carcinoma (Small Cell Lung Cancer)
12/2020 - 01/2020
3Brain Neoplasms (Brain Tumor)
01/2020 - 07/2015
3Adenocarcinoma
07/2018 - 07/2015

Drug/Important Bio-Agent (IBA)

14Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
02/2022 - 01/2014
14Pharmaceutical PreparationsIBA
01/2022 - 09/2014
13Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 08/2014
12selpercatinibIBA
01/2022 - 01/2020
11VemurafenibIBA
02/2022 - 08/2015
11pazopanibFDA Link
01/2021 - 06/2015
10Tyrosine Kinase InhibitorsIBA
01/2022 - 06/2015
9trametinibIBA
02/2022 - 01/2017
9pembrolizumabIBA
01/2022 - 01/2019
9Phosphotransferases (Kinase)IBA
01/2022 - 07/2011
8pralsetinibIBA
01/2022 - 01/2018
8vandetanib (ZD6474)IBA
01/2021 - 02/2015
8Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2014
8EverolimusFDA Link
01/2021 - 06/2015
8DNA (Deoxyribonucleic Acid)IBA
03/2020 - 06/2015
8TOR Serine-Threonine KinasesIBA
01/2018 - 08/2010
7Cell-Free Nucleic AcidsIBA
01/2020 - 01/2016
6CrizotinibIBA
10/2021 - 07/2011
6Immune Checkpoint InhibitorsIBA
01/2021 - 12/2017
6Bevacizumab (Avastin)FDA Link
01/2020 - 04/2016
6Proteins (Proteins, Gene)FDA Link
09/2018 - 01/2011
5Circulating Tumor DNAIBA
01/2022 - 10/2019
5dabrafenibIBA
01/2022 - 01/2018
5Radium-223IBA
10/2021 - 01/2014
5Cetuximab (Erbitux)FDA Link
01/2020 - 08/2015
5Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2019 - 08/2014
4selinexorIBA
04/2022 - 01/2021
4PM 01183IBA
01/2022 - 01/2020
4Biological ProductsIBA
01/2022 - 06/2013
4Immunoconjugates (Immunoconjugate)IBA
01/2022 - 01/2014
4PlatinumIBA
11/2021 - 08/2014
4RadiopharmaceuticalsIBA
10/2021 - 01/2014
4IpilimumabIBA
01/2021 - 01/2017
4GemcitabineFDA Link
01/2021 - 01/2018
4cabozantinibIBA
01/2021 - 01/2020
4VorinostatFDA Link
11/2020 - 10/2016
3AntibodiesIBA
01/2022 - 07/2011
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2022 - 04/2017
3ceritinibIBA
10/2021 - 03/2016
3RadiumIBA
10/2021 - 05/2015
3Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
10/2021 - 01/2016
3Hormones (Hormone)IBA
01/2021 - 01/2014
3Cisplatin (Platino)FDA LinkGeneric
01/2021 - 01/2018
3Histone Deacetylase InhibitorsIBA
11/2020 - 10/2016
3alovudineIBA
01/2020 - 04/2017
3Glucose (Dextrose)FDA LinkGeneric
01/2020 - 11/2015
3CreatinineIBA
01/2019 - 04/2008
3Imatinib Mesylate (Gleevec)FDA Link
01/2017 - 03/2010
3temsirolimusFDA Link
04/2016 - 01/2014
3ParaffinIBA
01/2016 - 04/2014
3Formaldehyde (Formol)FDA Link
01/2016 - 04/2014
2Topotecan (Hycamtin)FDA LinkGeneric
04/2022 - 10/2021
2Irinotecan (Camptosar)FDA LinkGeneric
01/2022 - 12/2016
2Transcription Factors (Transcription Factor)IBA
01/2022 - 03/2020

Therapy/Procedure

121Therapeutics
01/2022 - 07/2007
30Drug Therapy (Chemotherapy)
01/2022 - 11/2007
23Immunotherapy
01/2022 - 12/2017
8Precision Medicine
12/2021 - 03/2014
5Radiotherapy
01/2022 - 05/2012
4Time-to-Treatment
10/2021 - 10/2016
4Investigational Therapies (Experimental Therapy)
01/2021 - 04/2009
3Castration
01/2021 - 01/2014
3Neoadjuvant Therapy
10/2018 - 03/2010